MP37-19 AXIN2 EXPRESSION PREDICTS PROSTATE CANCER RECURRENCE AND MEDIATES AN INVASIVE, TUMORIGENIC PHENOTYPE
نویسندگان
چکیده
منابع مشابه
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
The androgen receptor (AR) is a key regulator of prostate tumorgenesis through actions that are not fully understood. We identified the repressor element (RE)-1 silencing transcription factor (REST) as a mediator of AR actions on gene repression. Chromatin immunoprecipitation showed that AR binds chromatin regions containing well-characterized cis-elements known to mediate REST transcriptional ...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2015
ISSN: 0022-5347,1527-3792
DOI: 10.1016/j.juro.2015.02.1282